Article
Target organ damage in African American hypertension: role of APOL1.
Current hypertension reports - 1 Feb 2012
Freedman Barry I, Murea Mariana
Abstract excerpt
Apolipoprotein L1 (APOL1) gene association studies and results of the African American Study of Kidney Disease and Hypertension are disproving the longstanding concept that mild to moderate essential hypertension contributes substantially to end-stage renal disease susceptibility in African Americans. APOL1 coding variants underlie a spectrum of kidney diseases, including that attributed to hypertension (labeled...
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