Article
APOL1 Risk Alleles Are Associated with Exaggerated Age-Related Changes in Glomerular Number and Volume in African-American Adults: An Autopsy Study.
Journal of the American Society of Nephrology : JASN - 1 Dec 2015
Hoy Wendy E, Hughson Michael D, Kopp Jeffrey B, Mott Susan A, Bertram John F, Winkler Cheryl A
Abstract excerpt
APOL1 genetic variants contribute to kidney disease in African Americans. We assessed correlations between APOL1 profiles and renal histological features in subjects without renal disease. Glomerular number (N glom) and mean glomerular volume (V glom) were measured by the dissector/fractionator method in kidneys of African-American and non-African-American adults without renal disease, undergoing autopsies in...
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