Article
APOL1 risk variants predict histopathology and progression to ESRD in HIV-related kidney disease.
Journal of the American Society of Nephrology : JASN - 1 Feb 2012
Fine Derek M, Wasser Walter G, Estrella Michelle M, Atta Mohamed G, Kuperman Michael, Shemer Revital, Rajasekaran Arun, Tzur Shay, Racusen Lorraine C, Skorecki Karl
Abstract excerpt
With earlier institution of antiretroviral therapy, kidney diseases other than HIV-associated nephropathy (HIVAN) predominate in HIV-infected persons. Outcomes for these diseases are typically worse among those infected with HIV, but the reasons for this are not clear. Here, we examined the role of APOL1 risk variants in predicting renal histopathology and progression to ESRD in 98 HIV-infected African Americans...
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