Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors.

doi:10.1523/JNEUROSCI.1526-14.2014

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Article

Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Jul 2014

Vukojevic Vanja, Kolassa Iris-T, Fastenrath Matthias, Gschwind Leo, Spalek Klara, Milnik Annette, Heck Angela, Vogler Christian, Wilker Sarah, Demougin Philippe, Peter Fabian, Atucha Erika, Stetak Attila, Roozendaal Benno, Elbert Thomas, Papassotiropoulos Andreas, de Quervain Dominique J-F

Abstract excerpt

Recent evidence suggests that altered expression and epigenetic modification of the glucocorticoid receptor gene (NR3C1) are related to the risk of post-traumatic stress disorder (PTSD). The underlying mechanisms, however, remain unknown. Because glucocorticoid receptor signaling is known to regulate emotional memory processes, particularly in men, epigenetic modifications of NR3C1 might affect the strength of...

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PMID: 25080589
DOI: 10.1523/JNEUROSCI.1526-14.2014
PMCID: PMC6608273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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