Article
The interplay between genetic variation and gene expression of the glucocorticoid receptor gene NR3C1 and blood cortisol levels on verbal memory and hippocampal volumes.
European archives of psychiatry and clinical neuroscience - 1 Dec 2022
Van der Auwera Sandra, Klinger-König Johanna, Wittfeld Katharina, Terock Jan, Hannemann Anke, Bülow Robin, Nauck Matthias, Völker Uwe, Völzke Henry, Grabe Hans Jörgen
Abstract excerpt
The hypothalamus-pituitary-adrenal axis is the main physiological stress response system and regulating the release of cortisol. The two corticoid receptors encoded by the genes NR3C1 and NR3C2 are the main players in regulating the physiological response to cortisol. This biological system has been linked to neurocognitive processes and memory, yet the mechanisms remain largely unclear. In two independent...
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