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Article

Tumor cells in search for glutamate: an alternative explanation for increased invasiveness of IDH1 mutant gliomas

28 Jul 2014

Abstract excerpt

With great interest we read the article “Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status” by Baldock et al.1 They describe a mathematical model of tumor growth based on MR imaging, which can determine proliferation and invasion of gliomas. In their study, they compared model-predicted growth profiles of a large series of contrast-enhancing gliomas with and without IDH1...

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PMID: 25074540
DOI: 10.1093/neuonc/nou152

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