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Article

Genetic architectures of ADME genes in five Eurasian admixed populations and implications for drug safety and efficacy.

Journal of medical genetics - 1 Sept 2014

Li Jing, Lou Haiyi, Yang Xiong, Lu Dongsheng, Li Shilin, Jin Li, Pan Xinwei, Yang Wenjun, Song Manshu, Mamatyusupu Dolikun, Xu Shuhua

Abstract excerpt

BACKGROUND: Drug absorption, distribution, metabolism and excretion (ADME) contribute to the high heterogeneity of drug responses in humans. However, the same standard for drug dosage has been applied to all populations in China although genetic differences in ADME genes are expected to exist in different ethnic groups. In particular, the ethnic minorities in northwestern China with substantial ancestry...

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PMID: 25074363
DOI: 10.1136/jmedgenet-2014-102530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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