Article
ADME pharmacogenetics: current practices and future outlook.
Expert opinion on drug metabolism & toxicology - 1 May 2009
Grossman Iris
Abstract excerpt
BACKGROUND: Genetic variants of ADME (absorption, distribution, metabolism and elimination) related genes have been consistently associated with pharmacokinetic properties of numerous drugs. However, the association between these genetic markers and clinical outcomes remains controversial. OBJECTIVE: Inform future pharmacogenetic ADME research and define the terms and practices for the utility of this approach....
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