Pharmacogenomics in admixed populations.

Abstract excerpt

Personalized drug therapy proffered by pharmacogenomics must be based on the recognition of inherent genetic individuality, rather than relying on inter-ethnic differences in the frequency of polymorphisms that affect the pharmacokinetics and targets of drugs. This is particularly significant in admixed populations, in which the substructure created by inter-ethnic crosses further increases the fluidity of racial...

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