Article
Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment.
Pharmacogenetics and genomics - 1 Oct 2014
Yi SoJeong, An Hyungmi, Lee Howard, Lee Sangin, Ieiri Ichiro, Lee Youngjo, Cho Joo-Youn, Hirota Takeshi, Fukae Masato, Yoshida Kenji, Nagatsuka Shinichiro, Kimura Miyuki, Irie Shin, Sugiyama Yuichi, Shin Dong Wan, Lim Kyoung Soo, Chung Jae-Yong, Yu Kyung-Sang, Jang In-Jin
Abstract excerpt
BACKGROUND: Interethnic differences in genetic polymorphism in genes encoding drug-metabolizing enzymes and transporters are one of the major factors that cause ethnic differences in drug response. This study aimed to investigate genetic polymorphisms in genes involved in drug metabolism, transport, and excretion among Korean, Japanese, and Chinese populations, the three major East Asian ethnic groups. METHODS:...
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