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Article

Pharmacogenomics, ancestry and clinical decision making for global populations.

The pharmacogenomics journal - 1 Jun 2014

Ramos E, Doumatey A, Elkahloun A G, Shriner D, Huang H, Chen G, Zhou J, McLeod H, Adeyemo A, Rotimi C N

Abstract excerpt

Pharmacogenomically relevant markers of drug response and adverse drug reactions are known to vary in frequency across populations. We examined minor allele frequencies (MAFs), genetic diversity (FST) and population structure of 1156 genetic variants (including 42 clinically actionable variants) in 212 genes involved in drug absorption, distribution, metabolism and excretion (ADME) in 19 populations (n=1478)....

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PMID: 23835662
DOI: 10.1038/tpj.2013.24

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FST
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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