Article
Polymorphisms in genes involved in the absorption, distribution, metabolism, and excretion of drugs in the Kazakhs of Kazakhstan.
BMC genetics - 19 Jan 2016
Iskakova Aisha N, Romanova Aliya A, Aitkulova Akbota M, Sikhayeva Nurgul S, Zholdybayeva Elena V, Ramanculov Erlan M
Abstract excerpt
BACKGROUND: Studies of genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are crucial to the development of therapeutics in clinical medicine. Such data provide information that may improve our understanding of individual differences in sensitivity or resistance to certain drugs, thereby helping to avoid adverse drug reactions (ADRs) in patients and improve the quality of...
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