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Article

Global patterns of genetic diversity and signals of natural selection for human ADME genes.

Human molecular genetics - 1 Feb 2011

Li Jing, Zhang Luyong, Zhou Hang, Stoneking Mark, Tang Kun

Abstract excerpt

Genetic polymorphisms in many genes related to drug absorption, distribution, metabolism and excretion (ADME genes) contribute to the high heterogeneity of drug responses in humans. However, the extent to which genetic variation in ADME genes may contribute to differences among human populations in drug responses has not been studied. In this work, we investigate the global distribution of genetic diversity for...

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PMID: 21081654
DOI: 10.1093/hmg/ddq498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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