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Article

A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans.

Journal of cardiovascular electrophysiology - 1 Nov 2014

Ilkhanoff Leonard, Arking Dan E, Lemaitre Rozenn N, Alonso Alvaro, Chen Lin Y, Durda Peter, Hesselson Stephanie E, Kerr Kathleen F, Magnani Jared W, Marcus Gregory M, Schnabel Renate B, Smith J Gustav, Soliman Elsayed Z, Reiner Alexander P, Sotoodehnia Nona

Abstract excerpt

OBJECTIVE: We examined the association of rs7626962 (S1103Y) or rs7629265, a variant in high linkage disequilibrium with S1103Y (r(2) = 0.87 - 1), with sudden cardiac death (SCD) and atrial fibrillation (AF) among African Americans. BACKGROUND: The SCN5A missense variant S1103Y has been associated with SCD among African Americans in small case-control studies, but larger population-based studies are needed to...

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Identifiers

PMID: 25065297
DOI: 10.1111/jce.12483
PMCID: PMC4454499

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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