Article
Population-Based Analysis of Rare Genetic Variants in Sudden Cardiac Arrest.
JACC. Clinical electrophysiology - 1 Aug 2026
Kransdorf Evan P, Mathias Marco, Nakamura Kotoka, Chugh Harpriya, Nguyen David, Tyrer Jonathan, Pharoah Paul D, Reinier Kyndaron, Akdemir Zeynep, Boerwinkle Eric, Yu Bing, Chugh Sumeet S
Abstract excerpt
BACKGROUND: More than 360,000 Americans experience sudden cardiac arrest (SCA) annually. A subgroup is caused by rare genetic variants, but existing studies are not population based and have been limited to nonsurvivors. OBJECTIVES: This study sought to establish the prevalence of disease-causing rare genetic variants in both survivors and nonsurvivors of SCA in the general population. METHODS: Patients with SCA...
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