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Article

Generation of an allelic series of knock-in mice using recombinase-mediated cassette exchange (RMCE).

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Roebroek Anton J M, Van Gool Bart

Abstract excerpt

Molecular genetic strategies applying embryonic stem cell (ES cell) technologies to study the function of a gene in mice or to generate a mouse model for a human disease are continuously under development. Next to (conditional) inactivation of genes the application and importance of approaches to generate knock-in mutations are increasing. In this chapter the principle and application of recombinase-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25064098
DOI: 10.1007/978-1-4939-1215-5_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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