Article
The association of genotype-based inbreeding coefficient with a range of physical and psychological human traits.
PloS one - 1 Jan 2014
Verweij Karin J H, Abdellaoui Abdel, Veijola Juha, Sebert Sylvain, Koiranen Markku, Keller Matthew C, Järvelin Marjo-Riitta, Zietsch Brendan P
Abstract excerpt
Across animal species, offspring of closely related mates exhibit lower fitness, a phenomenon called inbreeding depression. Inbreeding depression in humans is less well understood because mating between close relatives is generally rare and stigmatised, confounding investigation of its effect on fitness-relevant traits. Recently, the availability of high-density genotype data has enabled quantification of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.