Article
Five reasons why inbreeding may have considerable effect on post-reproductive human health.
Collegium antropologicum - 1 Dec 2004
Rudan Igor, Campbell Harry
Abstract excerpt
As the genetic architecture of common complex diseases of late onset is emerging through intensive research, it is intriguing to assess the predicted effect of inbreeding on those diseases. In this paper, we propose five reasons why we believe inbreeding may have a considerable effect on post-reproductive human health. (i) The joint effect of inbreeding depression on all polygenic quantitative phenotypes that...
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