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Article

Systematic analysis of gene properties influencing organ system phenotypes in mammalian perturbations.

Bioinformatics (Oxford, England) - 1 Nov 2014

Vogt Ingo, Prinz Jeanette, Worf Karolina, Campillos Monica

Abstract excerpt

MOTIVATION: Diseases and adverse drug reactions are frequently caused by disruptions in gene functionality. Gaining insight into the global system properties governing the relationships between genotype and phenotype is thus crucial to understand and interfere with perturbations in complex organisms such as diseases states. RESULTS: We present a systematic analysis of phenotypic information of 5047 perturbations...

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Identifiers

PMID: 25061072
DOI: 10.1093/bioinformatics/btu487
PMCID: PMC4609011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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