Article
PertOrg 1.0: a comprehensive resource of multilevel alterations induced in model organisms by in vivo genetic perturbation.
Nucleic acids research - 6 Jan 2023
Zhai Zhaoyu, Zhang Xuelu, Zhou Lu, Lin Zhewei, Kuang Ni, Li Qiang, Ma Qinfeng, Tao Haodong, Gao Jieya, Ma Shiyong, Pan Jianbo
Abstract excerpt
Genetically modified organisms (GMOs) can be generated to model human genetic disease or plant disease resistance, and they have contributed to the exploration and understanding of gene function, physiology, disease onset and drug target discovery. Here, PertOrg (http://www.inbirg.com/pertorg/) was introduced to provide multilevel alterations in GMOs. Raw data of 58 707 transcriptome profiles and associated...
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