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Article

Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases.

PloS one - 1 Jan 2011

Bauer-Mehren Anna, Bundschus Markus, Rautschka Michael, Mayer Miguel A, Sanz Ferran, Furlong Laura I

Abstract excerpt

BACKGROUND: Scientists have been trying to understand the molecular mechanisms of diseases to design preventive and therapeutic strategies for a long time. For some diseases, it has become evident that it is not enough to obtain a catalogue of the disease-related genes but to uncover how disruptions of molecular networks in the cell give rise to disease phenotypes. Moreover, with the unprecedented wealth of...

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PMID: 21695124
DOI: 10.1371/journal.pone.0020284
PMCID: PMC3114846

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