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Article

The orphan disease networks.

American journal of human genetics - 10 Jun 2011

Zhang Minlu, Zhu Cheng, Jacomy Alexis, Lu Long J, Jegga Anil G

Abstract excerpt

The low prevalence rate of orphan diseases (OD) requires special combined efforts to improve diagnosis, prevention, and discovery of novel therapeutic strategies. To identify and investigate relationships based on shared genes or shared functional features, we have conducted a bioinformatic-based global analysis of all orphan diseases with known disease-causing mutant genes. Starting with a bipartite network of...

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Identifiers

PMID: 21664998
DOI: 10.1016/j.ajhg.2011.05.006
PMCID: PMC3113244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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