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Article

DNA Mismatch Repair Abnormalities in Acinar Cell Carcinoma of the Pancreas

24 Jul 2014

Abstract excerpt

OBJECTIVES: Acinar cell carcinoma (ACC), including its mixed variants, is a rare pancreatic malignancy. Recent reports have documented its occurrence in Lynch syndrome. Our aim was to evaluate the frequency and clinicopathologic significance of DNA mismatch repair (MMR) deficiency in ACCs in general. METHODS: Mismatch repair protein expression was evaluated by immunohistochemistry in a series of 36 ACC cases that...

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PMID: 25058881
DOI: 10.1097/mpa.0000000000000190

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