Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas.

doi:10.1053/j.gastro.2017.11.009

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Article

Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Gastroenterology - 1 Mar 2018

Lupinacci Renato M, Goloudina Anastasia, Buhard Olivier, Bachet Jean-Baptiste, Maréchal Raphaël, Demetter Pieter, Cros Jérôme, Bardier-Dupas Armelle, Collura Ada, Cervera Pascale, Scriva Aurélie, Dumont Sylvie, Hammel Pascal, Sauvanet Alain, Louvet Christophe, Delpéro Jean-Robert, Paye François, Vaillant Jean-Christophe, André Thierry, Closset Jean, Emile Jean-François, Van Laethem Jean-Luc, Jonchère Vincent, Abd Alsamad Issam, Antoine Martine, Rodenas Anita, Fléjou Jean-François, Dusetti Nelson, Iovanna Juan, Duval Alex, Svrcek Magali

Abstract excerpt

Microsatellite instability (MSI) caused by mismatch repair deficiency (dMMR) is detected in a small proportion of pancreatic ductal adenocarcinomas (PDACs). dMMR and MSI have been associated with responses of metastatic tumors, including PDACs, to immune checkpoint inhibitor therapy. We performed immunohistochemical analyses of a 445 PDAC specimens, collected from consecutive patients at multiple centers, to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Cystic, Mucinous, and Serous

Source

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Identifiers

PMID: 29158190
DOI: 10.1053/j.gastro.2017.11.009

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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