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Article

c-MYC amplification and c-myc protein expression in pancreatic acinar cell carcinomas. New insights into the molecular signature of these rare cancers.

Virchows Archiv : an international journal of pathology - 1 Oct 2018

La Rosa Stefano, Bernasconi Barbara, Vanoli Alessandro, Sciarra Amedeo, Notohara Kenji, Albarello Luca, Casnedi Selenia, Billo Paola, Zhang Lizhi, Tibiletti Maria Grazia, Sessa Fausto

Abstract excerpt

The molecular alterations of pancreatic acinar cell carcinomas (ACCs) and mixed acinar-neuroendocrine carcinomas (MANECs) are not completely understood, and the possible role of c-MYC amplification in tumor development, progression, and prognosis is not known. We have investigated c-MYC gene amplification in a series of 35 ACCs and 4 MANECs to evaluate its frequency and a possible prognostic role. Gene...

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Identifiers

PMID: 29721608
DOI: 10.1007/s00428-018-2366-5

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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