Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunodominance Changes as a Function of the Infecting Dengue Virus Serotype and Primary versus Secondary Infection

23 Jul 2014

Abstract excerpt

UNLABELLED: Dengue virus (DENV) is the causative agent of dengue fever (DF). This disease can be caused by any of four DENV serotypes (DENV1 to -4) which share 67 to 75% sequence homology with one another. The effect of subsequent infections with different serotypes on the T cell repertoire is not fully understood. We utilized mice transgenic for human leukocyte antigens (HLA) lacking the alpha/beta interferon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25056881
DOI: 10.1128/jvi.01108-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunodominance Changes as a Function of the Infecting Dengue Virus Serotype and Primary versus Secondary InfectionPMID 25056881Read ↗

Dengue virus-reactive CD8+ T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes.Semantic proximity Read ↗

Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection.Semantic proximity Read ↗

Insights into HLA-Restricted T Cell Responses in a Novel Mouse Model of Dengue Virus Infection Point toward New Implications for Vaccine DesignSemantic proximity Read ↗

Cross‐Reactive Memory CD8+T Cells Alter the Immune Response to Heterologous Secondary Dengue Virus Infections in Mice in a Sequence‐Specific MannerSemantic proximity Read ↗

Understanding the contribution of cellular immunity to dengue disease pathogenesisSemantic proximity Read ↗

Differential Targeting of Viral Components by CD4<sup>+</sup>versus CD8<sup>+</sup>T Lymphocytes in Dengue Virus InfectionSemantic proximity Read ↗

Conserved MHC Class I–Presented Dengue Virus Epitopes Identified by Immunoproteomics Analysis Are Targets for Cross-Serotype Reactive T-Cell ResponseSemantic proximity Read ↗

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell responseSemantic proximity Read ↗

Human T Cell Response to Dengue Virus InfectionSemantic proximity Read ↗

Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cellsSemantic proximity Read ↗

HLA-DRB1 Alleles Are Associated With Different Magnitudes of Dengue Virus–Specific CD4 <sup>+</sup> T-Cell ResponsesSemantic proximity Read ↗

CD4+ T Cell Help Shapes Protective Humoral Immunity in Primary Dengue 2 Virus Infection: Implications for Rational Vaccine DesignSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.