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Article

Understanding the contribution of cellular immunity to dengue disease pathogenesis

19 Sept 2008

Abstract excerpt

SUMMARY: Dengue viruses (DENV) are the mosquito-borne viruses of greatest global public health importance. DENV circulate as four serotypes with significant immunologic cross-reactivity that does not provide protection from secondary infection with heterologous serotypes. The strong association of severe dengue illness, dengue hemorrhagic fever (DHF), with heterologous secondary infection and high cytokine levels...

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PMID: 18837790
DOI: 10.1111/j.1600-065x.2008.00678.x

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