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Article

Differential Targeting of Viral Components by CD4<sup>+</sup>versus CD8<sup>+</sup>T Lymphocytes in Dengue Virus Infection

20 Dec 2012

Abstract excerpt

Dengue virus (DENV) is the principal arthropod-borne viral pathogen afflicting human populations. While repertoires of antibodies to DENV have been linked to protection or enhanced infection, the role of T lymphocytes in these processes remains poorly defined. This study provides a comprehensive overview of CD4(+) and CD8(+) T cell epitope reactivities against the DENV 2 proteome in adult patients experiencing...

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PMID: 23255803
DOI: 10.1128/jvi.02675-12

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