Article
An association between MPO -463 G/A polymorphism and type 2 diabetes.
Folia biologica - 1 Jan 2014
Ergen A, Karagedik H, Karaali Z E, Isbir T
Abstract excerpt
Myeloperoxidase (MPO) is an enzyme which is a member of the haem-peroxidase superfamily and plays a role in production of reactive oxygen species. The most common polymorphism in the promoter region of MPO gene is -463 G/A. It was shown that carrying the GG genotype means increased activity of the gene approximately 2-3-fold compared to GA and AA genotypes. It was found that hyperglycaemia, modified oxidized...
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