Article
Functional polymorphism of the myeloperoxidase gene in hypertensive nephrosclerosis dialysis patients.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Dec 2007
Doi Kent, Noiri Eisei, Maeda Rui, Nakao Akihide, Kobayashi Shuzo, Tokunaga Katsushi, Fujita Toshiro
Abstract excerpt
Myeloperoxidase (MPO) may play an important role not only in host defense reactions but also in local inflammations, especially in atherosclerotic diseases such as hypertensive nephrosclerosis (HN). Paradoxically, MPO-deficient mice have been reported to show increased atherosclerosis compared wi...
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