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Article

Association of myeloperoxidase G-463A gene polymorphism with diabetic nephropathy in Japanese type 2 diabetic subjects.

Endocrine journal - 1 Jan 2013

Katakami Naoto, Kume Shinji, Kaneto Hideaki, Uzu Takashi, Kashiwagi Atsunori, Yamasaki Yoshimitsu, Maegawa Hiroshi, Shimomura Iichiro

Abstract excerpt

It is possible that myeloperoxidase (MPO) contributes to the pathogenesis of diabetic nephropathy through the production of reactive oxygen species and HOCl/OCl⁻. In this study, we examined the relationship between renal damage and MPO G-463A gene polymorphism that is associated with its transcription activity in diabetic patients. We evaluated the association between MPO G-463A polymorphism and the prevalence of...

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Identifiers

PMID: 23268804

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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