Article
Genetic determination of TNF and myeloperoxidase production in dialyzed patients with diabetic nephropathy.
Renal failure - 1 Nov 2004
Buraczynska Kinga, Koziol-Montewka Maria, Majdan Maria, Tokarz Agnieszka, Ksiazek Andrzej
Abstract excerpt
INTRODUCTION: Diabetic nephropathy accounts for more than 20% of the cases of chronic renal failure. For many patients, the method of renal replacement therapy is chronic ambulatory peritoneal dialysis (CAPD). Diabetes, through glucose autooxidation and production of free radicals, causes protein glycation. Products of protein glycation increase the concentrations of proinflammatory cytokines. The tumor necrosis...
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