Article
Evaluation of the oxidative stress-related genes ALOX5, ALOX5AP, GPX1, GPX3 and MPO for contribution to the risk of type 2 diabetes mellitus in the Han Chinese population.
Diabetes & vascular disease research - 1 Jul 2018
Liu Ding, Liu Lei, Hu Zhongyang, Song Zhi, Wang Yaqin, Chen Zhiheng
Abstract excerpt
AIM: Type 2 diabetes mellitus is a polygenic metabolic disorder resulting from oxidative stress, the root cause of insulin resistance, β-cell dysfunction and impaired glucose tolerance. The aim of this study was to investigate the role of oxidative stress-related genes ALOX5, ALOX5AP, GPX1, GPX3 and MPO in type 2 diabetes mellitus susceptibility in the Chinese Han population. METHODS: A total of 396 type 2...
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