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Article

Effects of myeloperoxidase -463 G/A gene polymorphism and plasma levels on coronary artery disease.

Molecular biology reports - 1 Feb 2011

Ergen Arzu, İsbir Selim, Timirci Özlem, Tekeli Atike, İsbir Turgay

Abstract excerpt

Myeloperoxidase is a lysosomal enzyme of polymorphonuclear leucocytes that contributes to inflammatory responses. In previous studies it was shown that MPO was synthesized in atherosclerotic lesions responsible of lipoprotein oxidations. We aimed to determine the MPO -463 G/A gene polymorphism distribution in Turkish population and evaluate the effects of it on myeloperoxidase levels. There were 100 myocardial...

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Identifiers

PMID: 20568015
DOI: 10.1007/s11033-010-0181-4

Genes

MPO
CAD

Provenance

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