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Article

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.

Development (Cambridge, England) - 1 Aug 2014

Osipovich Anna B, Long Qiaoming, Manduchi Elisabetta, Gangula Rama, Hipkens Susan B, Schneider Judsen, Okubo Tadashi, Stoeckert Christian J, Takada Shinji, Magnuson Mark A

Abstract excerpt

Insulinoma associated 1 (Insm1) plays an important role in regulating the development of cells in the central and peripheral nervous systems, olfactory epithelium and endocrine pancreas. To better define the role of Insm1 in pancreatic endocrine cell development we generated mice with an Insm1(GFPCre) reporter allele and used them to study Insm1-expressing and null populations. Endocrine progenitor cells lacking...

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Identifiers

PMID: 25053427
DOI: 10.1242/dev.104810
PMCID: PMC4197673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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