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Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

1 Dec 2018

Abstract excerpt

Human embryonic stem cells (hESCs) are a potential unlimited source of insulin-producing β cells for diabetes treatment. A greater understanding of how β cells form during embryonic development will improve current hESC differentiation protocols. All pancreatic endocrine cells, including β cells, are derived from Neurog3-expressing endocrine progenitors. This study characterizes the single-cell transcriptomes of...

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Pancreatic function and diabetes
Pluripotent Stem Cells Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30540962
DOI: 10.1016/j.stemcr.2018.11.008

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