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Article

Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.

Cancer research - 15 Sept 2014

Bera Soumen, Weinberg Frank, Ekoue Dede N, Ansenberger-Fricano Kristine, Mao Mao, Bonini Marcelo G, Diamond Alan M

Abstract excerpt

Glutathione peroxidase 1 (GPx-1) has been implicated in the etiology of several common diseases due to the association between specific allelic variations and cancer risk. The most common among these variations are the codon 198 polymorphism that results in either a leucine or proline and the number of alanine repeat codons in the coding sequence. The molecular and biologic consequences of these variations remain...

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Identifiers

PMID: 25047527
DOI: 10.1158/0008-5472.CAN-14-0660
PMCID: PMC4167490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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