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Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk.

Cancer research - 15 Nov 2000

Ratnasinghe D, Tangrea J A, Andersen M R, Barrett M J, Virtamo J, Taylor P R, Albanes D

Abstract excerpt

Human cellular glutathione peroxidase 1 (hGPX1) is a selenium-dependent enzyme that participates in the detoxification of hydrogen peroxide and a wide range of organic peroxides. We conducted a case-control study nested within the alpha-Tocopherol, beta-Carotene Cancer Prevention Study cohort to evaluate the association between the proline to leucine polymorphism at codon 198 of hGPX1 and lung cancer risk. Cases...

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PMID: 11103801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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