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Article

Loss of heterozygosity of the human cytosolic glutathione peroxidase I gene in lung cancer.

Carcinogenesis - 1 Dec 1994

Moscow J A, Schmidt L, Ingram D T, Gnarra J, Johnson B, Cowan K H

Abstract excerpt

The consistent deletion of 3p21 in lung cancer has led to intensive efforts to identify a lung tumor suppressor gene at this locus. We recently mapped the gene for the selenium-dependent drug-detoxifying enzyme glutathione peroxidase 1 (GPX1) to this location by in situ hybridization. We developed a polymerase chain reaction-based assay which demonstrated the existence of three GPX1 alleles characterized by the...

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Source

Identifiers

PMID: 8001233
DOI: 10.1093/carcin/15.12.2769

Genes

GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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