Donor NK cell licensing in control of malignancy in hematopoietic stem cell transplant recipients.

doi:10.1002/ajh.23802

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Article

Donor NK cell licensing in control of malignancy in hematopoietic stem cell transplant recipients.

American journal of hematology - 1 Oct 2014

Nowak Jacek, Kościńska Katarzyna, Mika-Witkowska Renata, Rogatko-Koroś Marta, Mizia Sylwia, Jaskuła Emilia, Polak Małgorzata, Mordak-Domagała Monika, Lange Janusz, Gronkowska Anna, Jędrzejczak Wiesław Wiktor, Kyrcz-Krzemień Sławomira, Markiewicz Mirosław, Dzierżak-Mietła Monika, Tomaszewska Agnieszka, Nasiłowska-Adamska Barbara, Szczepiński Andrzej, Hałaburda Kazimierz, Hellmann Andrzej, Komarnicki Mieczysław, Gil Lidia, Czyż Anna, Wachowiak Jacek, Barańska Małgorzata, Kowalczyk Jerzy, Drabko Katarzyna, Goździk Jolanta, Wysoczańska Barbara, Bogunia-Kubik Katarzyna, Graczyk-Pol Elżbieta, Witkowska Agnieszka, Marosz-Rudnicka Anna, Nestorowicz Klaudia, Dziopa Joanna, Szlendak Urszula, Warzocha Krzysztof, Lange And Andrzej

Abstract excerpt

Among cancers treated with allogeneic hematopoietic stem-cell transplantation (HSCT), some are sensitive to natural killer (NK) cell reactivity, described as the "missing self" recognition effect. However, this model disregarded the NK cell licensing effect, which highly increases the NK cell reactivity against tumor and is dependent on the coexpression of inhibitory killer cell immunoglobulin-like receptor...

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PMID: 25044365
DOI: 10.1002/ajh.23802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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