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Article

Allogeneic hematopoietic transplantation and natural killer cell recognition of missing self

7 Nov 2006

Abstract excerpt

Although the optimal donor for allogeneic hematopoietic stem cell transplantation (HSCT) is a human leukocyte antigen-matched sibling, 75% of patients do not have a match, and alternatives are matched unrelated volunteers, unrelated umbilical cord blood units, and full-haplotype-mismatched family members. To cure leukemia, allogeneic HSCT relies on donor T cells in the allograft, which promote engraftment,...

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Identifiers

PMID: 17100886
DOI: 10.1111/j.1600-065x.2006.00455.x

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