Article
Markers and function of human NK cells in normal and pathological conditions.
Cytometry. Part B, Clinical cytometry - 1 Mar 2017
Del Zotto Genny, Marcenaro Emanuela, Vacca Paola, Sivori Simona, Pende Daniela, Della Chiesa Mariella, Moretta Francesca, Ingegnere Tiziano, Mingari Maria Cristina, Moretta Alessandro, Moretta Lorenzo
Abstract excerpt
Natural killer (NK) cells, the most important effectors of the innate lymphoid cells (ILCs), play a fundamental role in tumor immune-surveillance, defense against viruses and, in general, in innate immune responses. NK cell activation is mediated by several activating receptors and co-receptors able to recognize ligands on virus-infected or tumor cells. To prevent healthy cells from auto-aggression, NK cells are...
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