Article
Prognosis after unmanipulated HLA-haploidentical blood and marrow transplantation is correlated to the numbers of KIR ligands in recipients.
European journal of haematology - 1 Apr 2007
Zhao Xiang-Yu, Huang Xiao-Jun, Liu Kai-Yan, Xu Lan-Ping, Liu Dai-Hong
Abstract excerpt
OBJECTIVES: The goal of this study was to explore the role of NK cell alloreaction in predicting prognosis under unmanipulated HLA-haploidentical blood and marrow transplantation and examine whether the presence of any individual donor-activating KIR gene had an influence on the clinical outcome. METHODS: We studied the HLA and KIR genotype of 64 donor-recipient pairs, who underwent transplantation. RESULTS: In...
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