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Article

Variants of the IL-10 gene associate with muscle strength in elderly from rural Africa: a candidate gene study.

Aging cell - 1 Oct 2014

Beenakker Karel G M, Koopman Jacob J E, van Bodegom David, Kuningas Maris, Slagboom Pieternella E, Meij Johannes J, Maier Andrea B, Westendorp Rudi G J

Abstract excerpt

Recently, it has been shown that the capacity of the innate immune system to produce cytokines relates to skeletal muscle mass and strength in older persons. The interleukin-10 (IL-10) gene regulates the production capacities of IL-10 and tumour necrosis factor-α (TNF-α). In rural Ghana, IL-10 gene variants associated with different production capacities of IL-10 and TNF-α are enriched compared with Caucasian...

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Source

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Identifiers

PMID: 25040424
DOI: 10.1111/acel.12244
PMCID: PMC4331746

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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