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Article

Interleukin-1 polymorphisms are associated with the inflammatory response in human muscle to acute resistance exercise.

The Journal of physiology - 1 Nov 2004

Dennis Richard A, Trappe Todd A, Simpson Pippa, Carroll Chad, Huang B Emma, Nagarajan Radhakrishnan, Bearden Edward, Gurley Cathy, Duff Gordon W, Evans William J, Kornman Kenneth, Peterson Charlotte A

Abstract excerpt

Inflammation appears to play an important role in the repair and regeneration of skeletal muscle after damage. We tested the hypothesis that the severity of the inflammatory response in muscle after an acute bout of resistance exercise is associated with single nucleotide polymorphisms (SNPs) previously shown to alter interleukin-1 (IL-1) activity. Using a double-blind prospective design, sedentary young men were...

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Identifiers

PMID: 15331687
DOI: 10.1113/jphysiol.2004.067876
PMCID: PMC1665272

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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