Article
Association of longevity with IL-10 -1082 G/A and TNF-alpha-308 G/A polymorphisms.
International journal of immunogenetics - 1 Aug 2010
Khabour O F, Barnawi J M
Abstract excerpt
Cytokines are crucial for the regulation of inflammation development in humans. Many studies have shown that variations in cytokine genes might play a role in determining human longevity. This study examined the changes in the gene pool relevant to the -308 G/A polymorphism in the promoter region of the proinflammatory cytokine tumour necrosis factor (TNF)-alpha gene and the -1082 G/A polymorphism in the promoter...
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