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Article

A modifier screen identifies regulators of cytoskeletal architecture as mediators of Shroom-dependent changes in tissue morphology.

Biology open - 3 Feb 2021

Hildebrand Jeffrey D, Leventry Adam D, Aideyman Omoregie P, Majewski John C, Haddad James A, Bisi Dawn C, Kaufmann Nancy

Abstract excerpt

Regulation of cell architecture is critical in the formation of tissues during animal development. The mechanisms that control cell shape must be both dynamic and stable in order to establish and maintain the correct cellular organization. Previous work has identified Shroom family proteins as essential regulators of cell morphology during vertebrate development. Shroom proteins regulate cell architecture by...

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Identifiers

PMID: 33504488
DOI: 10.1242/bio.055640
PMCID: PMC7875558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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