Article
Production of the Escherichia coli common pilus by uropathogenic E. coli is associated with adherence to HeLa and HTB-4 cells and invasion of mouse bladder urothelium.
PloS one - 1 Jan 2014
Saldaña Zeus, De la Cruz Miguel A, Carrillo-Casas Erika Margarita, Durán Laura, Zhang Yushan, Hernández-Castro Rigoberto, Puente José L, Daaka Yehia, Girón Jorge A
Abstract excerpt
Uropathogenic Escherichia coli (UPEC) strains cause urinary tract infections and employ type 1 and P pili in colonization of the bladder and kidney, respectively. Most intestinal and extra-intestinal E. coli strains produce a pilus called E. coli common pilus (ECP) involved in cell adherence and biofilm formation. However, the contribution of ECP to the interaction of UPEC with uroepithelial cells remains to be...
Topics
- Animals
- Bacterial Adhesion
- Biofilms
- Epithelial Cells
- Escherichia coli Proteins
- Fimbriae Proteins
- Fimbriae, Bacterial
- HeLa Cells
- Humans
- Mice
- Mutation
- Urinary Bladder
- Uropathogenic Escherichia coli