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Article

Roles of putative type II secretion and type IV pilus systems in the virulence of uropathogenic Escherichia coli.

PloS one - 1 Jan 2009

Kulkarni Ritwij, Dhakal Bijaya K, Slechta E Susan, Kurtz Zachary, Mulvey Matthew A, Thanassi David G

Abstract excerpt

BACKGROUND: Type II secretion systems (T2SS) and the evolutionarily related type IV pili (T4P) are important virulence determinants in many Gram-negative bacterial pathogens. However, the roles of T2SS and T4P in the virulence of extraintestinal pathogenic Escherichia coli have not been determined. METHODOLOGY/PRINCIPAL FINDINGS: To investigate the functions of putative T2SS and T4P gene clusters present in the...

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Identifiers

PMID: 19270734
DOI: 10.1371/journal.pone.0004752
PMCID: PMC2649431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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