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Commensal and pathogenic <i>Escherichia coli</i> use a common pilus adherence factor for epithelial cell colonization

12 Jun 2007

Abstract excerpt

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a food-borne pathogen that causes hemorrhagic colitis and the hemolytic uremic syndrome. Colonization of the human gut mucosa and production of potent Shiga toxins are critical virulence traits of EHEC. Although EHEC O157:H7 contains numerous putative pili operons, their role in the colonization of the natural bovine or accidental human hosts remains largely...

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PMID: 17563352
DOI: 10.1073/pnas.0704104104

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